RFLP Technique

RFLP Technique

Restriction Fragment Length Polymorphism (RFLP) is a technique in which organisms may be differentiated by analysis of patterns derived from cleavage of their DNA. If two organisms differ in the distance between sites of cleavage of a particular restriction endonuclease, the length of the fragments produced will differ when the DNA is digested with a restriction enzyme.

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RFLP
RFLP
Using RFLP, scientists cut specific portions of DNA into fragments for comparison. These fragments have different lengths, depending on the location of certain markers for cutting the DNA.
Relationship Test
Relationship Test
In a family relationship test, one person's DNA fragments are compared with those of an alleged relative. If the fragments match each other, they are considered to be from biologically related people.
Other DNA Familial Relationship Tests
Other DNA Familial Relationship Tests
DNA testing can definitively identify distant biological relationships. Our laboratory routinely performs DNA tests in cases of questioned grandparentage, siblingship, twin zygosity, maternity and more.
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