Mtdna Test
Mtdna Test

DNA EXAM of Bio-Synthesis the first company to provide commercial mtDNA testing services, has remained a major force in advancing biotechnology research both as leading supplier and developer of new technologies for paternity testing.

Our staff works hard to make the DNA Identity Testing Center your choice of provider for all DNA testing services. We ensure superior quality, service and convenience to our clients. In our commitment to providing convenience, please know that we provide a free DNASwabTM Home DNA Collection Kit for use in all types of private DNA tests.

Mitochondrial DNA
Mitochondrial DNA
Mitochondrial DNA (mtDNA) is the DNA located in organelles called mitochondria. Most other DNA present in eukaryotic organisms is found in the cell nucleus. Nuclear and mitochondrial DNA is thought to be of separate evolutionary origin, with the mtDNA being derived from the circular genomes of the bacteria that were engulfed by the early ancestors of today's eukaryotic cells.
Sperm mtDNA
Mechanisms for this include simple dilution (an egg contains 100,000 to 1,000,000 mtDNA molecules, whereas a sperm contains only 100 to 1000), degradation of sperm mtDNA in the fertilized egg, and, at least in a few organisms, failure of sperm mtDNA to enter the egg. Whatever the mechanism, this single parent (uniparental) pattern of mtDNA inheritance is found in most animals, most plants and in fungi as well. mtDNA is particularly susceptible to reactive oxygen species generated by the respiratory chain due to its close proximity.
DNA Repair
DNA Repair
mtDNA is packaged by proteins and harbors significant DNA repair capacity, these protective functions are less robust than those operating on nuclear DNA and therefore thought to contribute to enhanced susceptibility of mtDNA to oxidative damage. Mutations in mtDNA cause maternally inherited diseases and are thought to be a major contributor to aging and age-associated pathology.
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