Why a DNA Test Result Might Be Inconclusive?
DNA Test Results

The DNA Identity Testing Center of Bio-Synthesis, Inc. is an active member of the AABB Relationship Testing Accreditation Program and actively participates in proficiency testing by the College of American Pathologists. With nearly 15 years experience in the DNA testing field, law enforcement, legal representatives and individuals alike trust BSI with their private and legal DNA testing issues, worldwide.

Inconclusive Test Result
Inconclusive Test Result
DNA test will provide a conclusive result, whether it confirms a biological relationship or identifies an unknown sample. Sometimes, however, an inconclusive result may be obtained. some samples may not yield sufficient DNA profiles, which would mean that there would be a lack of sufficient data for use in calculating a conclusive result. Insufficient data may tend to come from non-standard or forensic evidence samples, which may be old or degraded. Time and storage conditions can greatly affect the viability of DNA samples. Usually, new samples must be obtained, if available, in order to determine a conclusive result or, perhaps, other, more sensitive testing methods may be utilized.
Test Results
Parentage Test
In a parentage test, specifically one between an alleged parent and child only, a mutation can sometimes be found. Mutations are differences in alleles, which usually vary by one unit, i.e. alleged parent has a 10 allele and the child has an 11 allele. Known mutations have a specific frequency in any given racial population. When that frequency is figured into the Probability of Parentage, it will lower that percentage and sometimes can cause it to fall below 99%. In this instance, it would be recommended to have the other, known parent provide a sample, or if that is not possible, perform extended testing to see if the Probability of Parentage increases.
Relationship Tests
Relationship Tests
In other relationship tests, like those between siblings or grandparents and grandchildren, the Probability of Relationship may fall into an inconclusive range. This is because these individuals have a second degree relationship and will likely share fewer similarities in their DNA profiles than would a parent and child (first degree relationship). If, for example, a siblingship test resulted in a 70% Probability of Relationship, it would be considered "uncertain" that the individuals would be related as such. If the individuals were, in fact, biological siblings, testing of their parent(s) would result in an increased Probability of Relationship, thereby confirming the fact that they were siblings. Extended testing of additional markers might also be an option for increasing Probability of Relationship in a situation like this.
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