DNA Probe Test
DNA Probe Test

Paternity web – www.paternityweb.com is the leading provider of confidential DNA probe testing services in the North America. Our technical team consists of the most experienced and highly qualified Ph.D level scientists in the field. The original and trusted name for discreet paternity testing. We perform 3 out of every 4 private tests and we are one of the largest and most experienced DNA testing facilities.

Our staff works hard to make the Paternity web – www.paternityweb.com your choice of provider for all DNA testing services. We ensure superior quality, service and convenience to our clients. In our commitment to providing convenience, please know that we provide a free DNASwabTM Home DNA Collection Kit for use in all types of private DNA tests.

Hybridization Probe
Hybridization Probe
In molecular biology, a hybridization probe is a fragment of DNA of variable length (usually 100-1000 bases long), which is used to detect in DNA or RNA samples the presence of nucleotide sequences (the DNA target) that are complementary to the sequence in the probe. The probe thereby hybridizes to single-stranded nucleic acid (DNA or RNA) whose base sequence allows probe-target base pairing due to complementarity between the probe and target. The labeled probe is first denatured (by heating or under alkaline conditions) into single DNA strands and then hybridized to the target DNA (Southern blotting) or RNA (northern blotting) immobilized on a membrane or in situ.
DNA Sequences
DNA sequences or RNA transcripts that have moderate to high sequence similarity to the probe are detected by visualizing the hybridized probe via autoradiography or other imaging techniques. Detection of sequences with moderate or high similarity depends on how stringent the hybridization conditions were applied — high stringency, such as high hybridization temperature and low salt in hybridization buffers, permits only hybridization between nucleic acid sequences that are highly similar, whereas low stringency, such as lower temperature and high salt, allows hybridization when the sequences that are less similar.
DNA Microarrays
DNA Microarrays
Hybridization probes used in DNA microarrays refer to DNA covalently attached to an inert surface, such as coated glass slides or gene chips, and to which a mobile cDNA target is hybridized.
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